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This Concept Map, created with IHMC CmapTools, has information related to: CBL A1 Ethel Kardashian, macrocytic anemia as indicated by MCV, glucose release into blood, Thiamine decreases formation of Thiamine Pyrophosphate, Thiamine Pyrophosphate which inhibits reactions, malate decreasing gluconeogenesis, Pyruvate to Acetyl CoA, NADH:NAD+ decreasing TCA cycle, acetaldehyde oxidized to acetate, production of ATP via oxidative phosphorylation, alpha-ketoglutarate dehydrogenase complex decarboxylates alpha-ketoglutarate, NADH:NAD+ increasing conversion of Pyruvate, Thiamine has active form Thiamine Pyrophosphate, Ethel Kardashian tested positive for macrocytic anemia, blood glucose level inhibiting proper functioning of brain, Succinyl CoA + CO2 intermediates in production of ATP, fasting state with low glycogen stores in liver, acetate in hepatic mitochondria, gluconeogenesis leading to decrease in blood glucose level, near syncope episode at work, coenzyme in alpha-ketoglutarate dehydrogenase complex